podcast

Episode 14- Interview with Dr. Mark Rego on Frontal Fatigue | The Generation Zen Podcast

Monday, February 2, 2026

Dr. Rego has practiced adult, adolescent and geriatric psychiatry for 30 years. He spent 25 years in community practice specializing in treating patients who required medications, helping people who were poorly responsive to usual treatment, and addressing the special needs of those in hospitals, nursing homes, group homes and outpatients with medical problems.  

Since he began practice in 1989 he has taught psychiatric trainees at Yale New Haven Hospital and was the first member of his department to have psychiatric residents sit with him and observe patient care directly.

Currently he is researching and writing about the intersection between modern life and issues relevant to mental health. His publications can be found on Medium.com (⁠https://mdrmd2.medium.com/⁠) and other sites. 

Dr. Rego presently consults to small community clinics who treat the under-served. He continues to teach at Yale New Haven Hospital.

Show notes:

00:01-02:23- Intro

02:24-10:57- What is Frontal Fatigue? 

10:58-15:49- Relationship between Spirituality and Prefrontal Fatigue

15:50-23:59 Prefrontal Cortex and stress

24:00-29:59 What does an evolved PFC look like?

30:00-33:59 Relationship with Nature

34:00-37:59 The importance of getting in touch with the present

38:00-40:51 Role of meditation and yoga, Default mode network activities

40:52-43:59 Zen Buddhism

44:00-46:31 Advice for the next generation

Links:

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